Advances in Clinical Chemistry by Gregory S. Makowski (Eds.)

By Gregory S. Makowski (Eds.)

Quantity forty nine within the across the world acclaimed Advances in medical Chemistry comprises chapters submitted from prime specialists from academia and scientific laboratory technology. Authors are from a various box of scientific chemistry disciplines and diagnostics starting from simple biochemical exploration to state-of-the-art microarray know-how. * top specialists from academia and scientific laboratory technology * quantity emphasizes novel laboratory advances with program to medical laboratory diagnostics and useful uncomplicated technology reviews

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2. Glycoxidation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3. Amino Acid Modifications. . . . . . . . . . . . . . . . . . . . . . . . . 8. Biomarkers of Collagen Oxidative Damage . . . . . . . . . . . . . . . . . . . 1. Glycoxidation Products. . . . . . . . . . . . . . . . . . . . . . . . . . 2. Nitrated Peptides . . . . . .

Middleton et al. [95] suggested that it is unlikely that minor elevations in cTnI or cTnT subsequent to endurance exercise are due to myocardial necrosis. These authors hypothesized that postexercise troponin release represents the reversible cardiomyocyte membrane damage during remodeling processes [95]. According to this hypothesis, in a healthy exercising population, cardiac troponins may be routinely released after periods of increased myocardial demand, such as after endurance exercise. As mentioned earlier, recently developed methods for cTnI and cTnT assays may be able to detect a release of protein from a quantity of myocardial tissue of a few milligrams in size [20–30] (Table 1).

4. In Vivo Production of RNOS . . . . . . . . . . . . . . . . . . . . . . . . . . 5. RNOS Biological Activity . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6. In Vivo Markers of Oxidant Stress. . . . . . . . . . . . . . . . . . . . . . . . 7. Oxidant-Induced Changes in Collagens . . . . . . . . . . . . . . . . . . . . . 1. Oxidative Cleavage .

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